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Oncolex is an encyclopedia for oncology health personnel. Here you will find background information and updated procedures for the diagnosis and treatment of cancer. Read >>

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Gynecologic Cancer02.03.17

Trophoblastic diseases originate during pregnancy, and consequently contain genetic material, which is foreign for the woman. The disease can occur after normal pregnancy, ectopic pregnancy, as well as spontaneous and induced abortion. 

During fertilization, trophoblastic cells invade the endometrium, blood vessels and myometrium to establish fetomaternal circulation.  In a normal pregnancy, a large number of trophoblasts circulate in the mother's blood system. In trophoblastic diseases, there is uninhibited invasion of trophoblasts in the mother's myometrium and blood system. The cancer type is revised >>>

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