The prognosis depends on whether the anal cancer is localized, regional, or metastatic at the time of diagnosis. 48.2% are diagnosed at the local stage and the 5-year survival for localized anal cancer is 81.3%. The overall 5-year survival rate for anal cancer patients during the period 2007-2013 was 66.9%.
Death rates have been rising on average 2.9% each year over 2005-2014. The percent of anal cancer deaths is highest among people aged 55-64. The number of deaths was 0.2 per 100,000 men and women per year based on 2010-2014 deaths and in 2017 there are an estimated 1,100 people will die of this disease (2).