Bile duct cancer usually manifests itself by jaundice, possibly accompanied by change in general health status. Pain is often absent and is first observed in an advanced stage.
Inflammation of the bile ducts (cholangitis) is more uncommon as a debut symptom. Weight loss and other general health symptoms may indicate a more advanced stage.
Symptoms of gallbladder cancer often first develop at an advanced stage.
Symptoms may be pain similar to plain gallstone disease, and change in character:
- discomfort and pain in the upper abdomen and right subcostal area during meals
- pain radiating towards the right shoulder blade