Anne Grete Bechensteen MD
Recently updated 05.08.2010
Oslo University Hospital
Antiemetic treatment should be started before the chemotherapy.
- For moderate emetic activity - give ondansetron intravenously or orally 15-30 minutes before starting and thereafter 2-3 times daily. Tropisetron may be given once daily for children > 10 years.
- For high emetic activity - give ondansetron intravenously 15 minutes before starting chemotherapy. Repeat after 2-4 hours and thereafter every 8 hours. Dexamethazone is given together with the first dose of ondansetron (only once).
- In special cases, these can be tried:
- dexchlorpheniramine orally or intravenously
- promethazine orally or intravenously
- diazepam orally or intravenously x 2–3 times daily
- chlorpromazine orally
- For intensive nausea, antiemetics should be given regularly until the day after chemotherapy is finished.
- For chemotherapy drugs causing delayed nausea, the antiemetic treatment should be extended 3-5 days after concluded chemotherapy treatment.
- Good hydration can help to soothe nausea.
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