Locally advanced colon cancer grows into surrounding organs. Which organs that are involved depends on the location of the cancer. Due to its mobility, sigmoid colon cancer often grows into the pelvic organs. This can also occur when the cecum is mobile and in rare cases in a very long transverse colon.
When there is infiltration into essential structures such as veins, nerves, and bone of the posterior abdominal wall, it may be appropriate to administer pre- or postoperative radiation. The advantage of postoperative radiation is that the area with highest risk of recurrence is identified and can be marked with clips during surgery to reduce the radiation field as much as possible.
The condition is often combined with peritoneal carcinomatosis which will be a contraindication to extensive surgery.
A palliative resection may be appropriate if the condition clearly influences quality of life.
- Colon cancer (locally advanced/local relapse)
- Improve/ prevent extensive reduction of life quality