In most cases, the causes are unknown. However, the development of esophageal cancer is observed in connection with different risk factors.
Spinocellular cancer is related to:
- corrosion damage (exposure to solvents and corrosive chemicals)
Adenocarcinomas are related to:
- Obesity, with increasing frequency of reflux esophagitis
- Intestinal metaplasia (Barrett’s esophagus), which is a result of esophagitis.