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Surgery of gestational trophoblastic disease

In older patients without fertility wishes, a hysterectomy may be considered for localized disease.

Placental-site trophoblastic tumors are treated primarily by hysterectomy since these tumors are relatively chemo-resistent. Metastases from placental-site tumors are treated by surgical extirpation if possible, often in combination with cisplatin-based combination chemotherapy. 

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