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Prognosis of uterine cancer

 

Five-year relative survival for patients with uterine cancer, in percent, according to stage and diagnosis period 1974–2013.

Source: Cancer Registry of Norway

 

Five-year survival for patients treated during 1993–95  

Patients treated during 1993–95 (22)

Ia 89 %
Ib 90 %
Ic 81 %
IIa 80 %
IIb 72 %
IIIa 63 %
IIIb 39 %
IIIc 51 %
IVa 20 %
IVb 17 %

In addition to stage, the grade of differentiation and histological type are significant.

Seropapillary and clear cell tumors have a high risk for recurrence, even if in stage Ia. These tumors therefore belong to high risk groups (9).

Five-year survival for endometroid type stage I relative to grade of differentiation

Relative to grade of differentiation (22
High = G1 92 %
Moderate = G2 90 %
Low = G3 74 %

Five-year survival for endometrioid type stage I relative to depth of invasion into the myometrium

Relative to depth of invasion (21)
 
Intramucosal 90 %
< 50 % 82 %
> 50 % 62 %
T1 serosa 49 %

For endometrioid-type tumors, the association between grade of differentiation and myometrial invasion can be derived below.  

Risk grouping for stage I
Stage Differentiation grade
G1 = High G2 = Moderate G3 = Low
la Low Low Moderate
lb Low           Low Moderate
lc Moderate Moderate High

 

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