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Diagnostics of laryngeal cancer

The patient's primary care doctor usually examines the patient first.

The clinical examinations should include:

  • thorough inspection of the mucosa of the mouth, pharynx, and larynx
  • thorough palpation of the neck for enlarged lymph nodes

For suspected malignancy, the patient should be immediately referred to an ENT specialist/clinic.

At Oslo University Hospital, the following examinations are performed according to the UICC certainty level C2 (4).

  • Clinical examination 
  • Chest CT
  • CT/MRI of primary tumor area and neck. These examinations give objective measurements for primary tumor and metastases, the examination is necessary to determine the extent of surgery and modeling of the radiation field (except for T1a).
  • Flexible endoscopy, possibly with loop laryngoscopy and microlaryngoscopy with biopsy.
  • Fine needle cytology, possibly with ultrasound

Possible additional examinations:

  • Blood tests to evaluate T4, TSH, liver and kidney function
  • Chest CT in patients with suspected lung metastases/lung tumor 
  • Broncho- or esophagoscopy for suspected lung metastases/lung tumor (not obligatory)
  • If needed, the patient is evaluated by a lung specialist, cardiologist or other specialists for operability.
  • Examination by an oral surgeon/maxillofacial surgeon

The staging form is completed and the patient is evaluated by an interdisciplinary team including a head/neck surgeon, oncologist, pathologist, radiologist, and cancer nurse.

Recurrence

Evaluation for recurrence is the same as for a primary tumor.

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