The risk for recurrence after surgery alone varies according to localization.
Radiation therapy is directed against the area of the tumor because there is often microscopic residual disease despite "free" resection margins evaluated by light microscopy. In addition, regional lymph nodes are irradiated either for manifest regional metastases or because of the primary tumor's localization, and/or the T stage suggests high probability for microscopic disease in regional lymph nodes.
The target volume and dose are adapted for each patient.
- Remove microscopic residual disease and prevent and/or eradicate spreading to cervical lymph nodes.