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Etiology of cancer of the nasal cavity and paranasal sinuses

  • Human papilloma virus (HPV) (2) may play a role in inverted papilloma but its role in squamous cell carcinoma is uncertain.
  • Beeing exposed to nickel at work increases the risk for developing squamous cell carcinoma (8).
  • Beeing exposed to dust from hardwood or dust from leather goods increases the risk for adenocarcinoma (9).

Tobacco is a possible etiological factor (2). The effect snuffing tobacco has on development of cancer is not sufficiently documented. 

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