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Prognosis of cancer of the nasal cavity and paranasal sinuses

Patients with early stages (T1–T2, N0) of squamous epithelial carcinomas in the nose and sinuses have a relatively good prognosis, but this rarely occurs. Long-term survival is reduced with locally advanced disease (T3–T4), as well as with the presence of lymph node metastases in the neck.

With spreading of lymph nodes in the neck, the disease-specific survival is reduced by 50% compared to the same T-stage without lymph-node metastasis. Increasing N-category also increases the risk for distant metastases.

Confirmed distant metastasis at present usually eliminates curative treatment. The five-year survival for patients with for locoregional recurrence is 20% (6).

 

 

Five-year relative survival for patients with cancer in the nasal cavity and paranasal sinuses, in percent, during the diagnosis period 1974–2013.

Source: Cancer Registry of Norway

 

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