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Kidney cancer

Kidney (renal cell) cancer originates mainly from proximal tubular epithelial cells, but also from cells from intercalated and medullary collecting ducts. There are multiple types of kidney cancer, but clear cell renal cell carcinoma is the most common (around 85%). The histological subgroups are chromophobe and papillary renal cell carcinoma, often with a percentage of malignant mesenchymal cells (sarcomatoid differentiation) (2).


Compared to other cancers, kidney and renal pelvis cancer is fairly common and represents 3.7% of all new cancer cases in the United States. Kidney and renal pelvis cancer is most frequently diagnosed among people aged 65-74 and is more common in men than women.

In 2016, it was estimated to be 62,700 new cases of kidney and renal pelvis cancer in the United States (15).


Age-specific incidence of kidney cancer (not including renal pelvis), 2009–2013.

Source: Cancer Registry of Norway



Incidence of kidney cancer (not including renal pelvis), 1954–2013.

Source: Cancer Registry of Norway


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