Many CML patients are diagnosed before they develop symptoms during health checks or routine blood tests. Leukocytosis and an enlarged spleen cause suspicion of the disease.
Patient history and clinical examinations
Survey general leukemia symptoms and hyperviscosity symptoms which can occur in chronic myeloid leukemia.
- Leukocytes with differentiation
- Uric acid
- Liver tests
- Renal function tests
- BCR-ABL mutation analysis
Bone marrow aspirate/biopsy
- Morphological assessment
- Cytogenetic examination