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Differential diagnoses of liver cancer

The differential diagnosis for primary liver cancer is other tumor types in the liver:

  • Cystadenocarcinoma in intrahepatic bile ducts
  • Hepatoblastoma (children)
  • Undifferentiated carcinoma
  • Epitheloid hemangioendothelioma
  • Angiosarcoma
  • Embryonal sarcoma (children)
  • Rhabdomyosarcoma
  • Metastasis from other primary tumors

Benign tumors: 

  • Hemangiomas
  • Focal nodular hyperplasia
  • Hamartoma (von Meyenburg complex)
  • Angiomyolipoma

Regenerating nodules from liver cirrhosis are another differential diagnosis.

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