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Symptoms of non-Hodgkin lymphoma

There are three symptoms associated with lymphoma:

  • night sweats - defined based on wet bed linens that must be changed multiple times in the last month
  • fever - unexplained raise in temperature over 38°C for at least one week
  • weight loss - unexplained weight reduction of more than 10% of body weight during the last 6 months

If one or more of these symptoms are present, it is denoted as a "B symptom". B symptoms occur in less than 40% of patients with aggressive NHL and in 20  %of indolent NHL.

Other symptoms may be:

  • itchy skin
  • repeated infections
  • bleeding tendency

Findings

  • Enlarged lymph nodes on the neck, axilla, or groin.
  • Abdominal distension. Lymphoma manifestation can block intestinal passage, which can lead to nausea, vomiting, and pain in the abdomen.
  • Urine blockage by compression of kidneys and urinary tracts. Symtoms of this may be a small amount of urine, fatigue, poor appetite, nausea, or swelling of hands and feet.
  • Back pain, which is a symptoms of cross-sectional lesion with spinal compression.
  • Lymphoma in the mediastinum can lead to compression of airways which can lead to dyspnea and coughing.
  • Pressure on the superior vena cava may lead to expanded neck veins, swelling of the neck, bulging eyes, and cyanosis in certain cases.

Findings vary based on localization of tumor.

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