There are three symptoms associated with lymphoma:
- night sweats - defined based on wet bed linens that must be changed multiple times in the last month
- fever - unexplained raise in temperature over 38°C for at least one week
- weight loss - unexplained weight reduction of more than 10% of body weight during the last 6 months
If one or more of these symptoms are present, it is denoted as a "B symptom". B symptoms occur in less than 40% of patients with aggressive NHL and in 20 %of indolent NHL.
Other symptoms may be:
- itchy skin
- repeated infections
- Enlarged lymph nodes on the neck, axilla, or groin.
- Abdominal distension. Lymphoma manifestation can block intestinal passage, which can lead to nausea, vomiting, and pain in the abdomen.
- Urine blockage by compression of kidneys and urinary tracts. Symtoms of this may be a small amount of urine, fatigue, poor appetite, nausea, or swelling of hands and feet.
- Back pain, which is a symptoms of cross-sectional lesion with spinal compression.
- Lymphoma in the mediastinum can lead to compression of airways which can lead to dyspnea and coughing.
- Pressure on the superior vena cava may lead to expanded neck veins, swelling of the neck, bulging eyes, and cyanosis in certain cases.
Findings vary based on localization of tumor.