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Hepatosplenic T-cell lymphoma

This is a systemic, extra nodal neoplasia involving the liver, spleen, bone marrow, and consists of cytotoxic T-cells (CD3+, CD4-, CD8-, TIA-1+, TCRgd+). Isochromosome 7q is a characteristic cytogenetic finding that may be helpful diagnostically.

The disease course is aggressive and remissions are often short. 

Treatment

See the information given about T-cell lymphoma.

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