Symptoms and findings of multiple myeloma
Symptoms and findings are caused by the localization of myeloma cells in bone marrow and the effect of the M-component (paraprotein).
- Bone pain
- Reduced renal function
- Anemia, more rarely leukopenia and thrombocytopenia
- Hypercalcemia due to osteolysis
- Repeated bacterial infections due to reduced immune system
- Neuralgia, paralysis, and numbness
- Signs of amyloidosis, for example large tongue, carpal tunnel syndrome, kidney and/or heart failure
- Prolonged elevated blood sedimentation rate.
|MRI of patient with myeloma in spine. Click to enlarge image.
||MRI of patient with destruction and collapse of vertebra. Click to enlarge image.
||X-ray of patient with pathological fracture in humerus. Click to enlarge image.