Medicament |
Common reactions |
Remedial action |
Dakarbazin (DTIC)
|
Phototoxic/photoinstability
|
See general precautions
|
Redness in skin, tingling of the scalp and general unwellness
|
Avoid sunlight completely the day of the treatment (9)
|
Methotrexate
|
Phototoxic
|
See general precautions
|
Acne-like rash
|
Avoid direct sun exposure, heat and humidity (9,10). Avoid soap, alcohol based skin products (9). Use moisturizing products and oil bath (4,9,10). |
Palmoplantar erythrodysesthesia = Acral erythema (PPE) |
Preventive: Pyridoxin (vitamine B6) (2,6,9)
Avoid sunlight, heat, pressure against the skin and tight clothing can according to some studies have an effect (11,12,13). Use moisturizer.
Treatment/relief: Cortisone salves, cortisone tablets, cold compress, cold baths
(2, 9) |
Fluorouracil (5-FU®)
|
Phototoxic |
See general precautions
|
Palmoplantar erythrodysesthesia = Acral erythema (PPE) |
Preventive: Pyridoxin (vitamin B6) (2,6,9)
Avoid sunlight, heat, pressure against the skin and tight clothing can according to some studies have an effect (11,12,13). Use moisturizer.
Treatment/relief: Cortisone salves, cortisone tablets, cold compress, cold baths (2, 9)
|
Radiation recall
|
Treatment as with phototoxic
|
Kapecitabin (Xeloda®)
|
Phototoxic |
See general precautions |
Palmoplantar erythrodysesthesia = Acral erythema (PPE) |
Preventive: Pyridoxin (vitamin B6) (2, 6, 9). Preventive: Pyridoxin (vitamin B6) (2, 6, 9)
Avoidance of sunlight, heat, pressure against the skin and tight clothing can according to some studies have an effect (11,12,13). Use moisturizer.
Treatment/relief: Cortisone salves, cortisone tablets, cold compress, cold baths (2, 9) |
Vinblastin
|
Phototoxic
|
See general precautions
|
Radiation recall |
Treatment as with phototoxic
|
Doxorubicin liposomal (Caelyx®)
|
Palmoplantar erythrodysesthesia = Acral erythema (PPE) |
Preventive: Pyridoxin (vitamin B6) (2, 6, 9)
Avoidance of sunlight, heat, pressure against the skin and tight clothing can according to some studies have an effect (11,12,13). Use moisturizer.
Treatment/relief: Cortisone salves, cortisone tablets, cold compress, cold baths (2, 9)
|
Tegafur
|
Phototoxic
|
See general precautions
|
Palmoplantar erythrodysesthesia = Acral erythema (PPE) |
Preventive: Pyridoxin (vitamin B6) (2, 6, 9)
Avoidance of sunlight, heat, pressure against the skin and tight clothing can according to some studies have an effect (11,12,13). Use moisturizer.
Treatment/relief: Cortisone salves, cortisone tablets, cold compress, cold baths (2, 9)
|
EGFR-hemmere
(Cetuximab, panitumab, erlotinib, gefitinib, lapatinib, vandetanib)
|
Phototoxic
|
See general precautions
|
Acne-like rash
|
Avoid direct sun exposure, heat and humidity (9,10). Avoid soap, alcohol based skin products (9). Use moisturizing products and oil bath(4, 9, 10).
|