Bone marrow stimulation with G-CSF (Neupogen®, Granocyte®) is only recommended for febrile neutropenia which does not respond to antibiotic treatment, severe neutropenia (granulocytes < 0.5 x 109 /L for more than 1 week), and in cases where it is necessary to administer curative treatment with sufficient dosage intensity.
- To maintain dosage intensity for curative treatment; when a reduction in dosage will significantly reduce the chance of cure.
- As prophylaxis for treatments associated with a high risk for febrile neutropenia (> 40 %)
- Febrile neutropenia that does not respond quickly to antibiotic treatment
- Long-lasting neutropenia
- Maintain treatment intensity