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Endoscopic Ultrasound with Aspiration

Medical editor Lars Aabakken MD

Oslo University Hospital


The location of the tumor or lymph node in the mediastinum determines whether an endoscopic ultrasound-guided fine needle aspiration (EUS) from the esophagus or endobronchial ultrasound (EBUS) should be performed.

EUS with aspiration of lymph nodes in the mediastinum is a minimally invasive examination whereby patients can avoid examinations associated with more risk. With EUS, the mediastinal lymph nodes can be sampled at most levels of the mediastinum. 


  • Enlarged lymph nodes and/or tumor in the mediastinum raising suspicion of a serious lung disease, cancer in the esophagus or stomach. 


  • Establish a diagnosis 
  • Stage determination


  • Endoscope with accessories
  • Needle for puncture
  • Equipment for preparation of cytology specimen


  • The patient lies on his/her side and is mildly sedated.
  • Application of local anesthesia in the throat.  


  • The scope is inserted into the esophagus via a mouthpiece. 
  • The lymph nodes are visualized using ultrasound.
  • The aspiration needle is inserted through the work channel of the scope and by ultrasound guidance, into the lymph node.
  • Using back-and-forth movements with the needle, cells are sucked out of the lymph node.
  • The material is prepared and assessed by a cytologist.
  • The procedure can be repeated until representative material is obtained.


  • The patient can return home the same day.
  • It may take up to one week before the results are available.

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