Punch biopsy for penile cancerMedical editor Bjørn Brennhovd MD
Oslo University Hospital
With superficial tumors (Tis-T1), it is clinically impossible to assess the depth of infiltration without performing a punch biopsy. In order to safely choose organ-saving surgery, it is necessary to know whether the tumor is infiltrating and how deeply it expands.
With advanced penile cancer (T2-T4), determination of the depth of infiltration is not problematic.
A biopsy from the glans or prepuce may be done under local anesthesia.
- biopsy punch with needle
- local anesthesia
- Inject the local anesthesia at the base of the tumor.
- Resect a biopsy with a 2 or 4 mm needle.
- Retrieve the cylindrical biopsy tissue.
- Mark the superficial end of the biopsy tissue.
- If necessary, insert a suture.
- Request for the depth of infiltration in the referral to the pathologist.
- Consult with the patient when the histology result is available.