For patients with infiltration through the capsule (pT3) and microscopic involved margins after prostatectomy, it is additional radiation therapy is given. This is performed as external radiation.
This type of treatment is given to reduce the local relapse frequency, but has no definite effect on survival. Multiple studies are in progress to identify alternative methods of treatment for this patient group. It may also be an alternative for these patients to await the rise of the PSA-level in the serum postoperatively before radiation therapy is started. Preferably, this should be done before the level has increased above 1 ng/ml.
- Previous prostatectomy
- pT3 or involved resection margins
- Rising serum PSA (< 1 ng/ml) after prostatectomy