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Primary external radiation therapy for prostate cancer

General

External radiation therapy to the prostate is completed as 4-field conformal (organ configured) radiation therapy.

Conformal radiation therapy distinguishes itself from conventional radiation therapy by delivering a higher dose toward a reduced target volume. This provides a reduced toxicity to the neighboring structures (rectum, bladder, nerves).

It can be appropriate to give hormone treatment in addition to radiation treatment in patients where:

  • Volume of the prostate is great (> 60 cc)
  • The tumor has grown through the capsule (T3) and/or PSA > 20 and/or Gleason score ≥ 8

Goal

  • Curative treatment

Indications

  • T1/T2 pN0, PSA ≤ 20
  • T1/T2 pN0, Gleasonscore ≥ 8
  • T2 pN0, 20 < PSA < 70
  • T3 pN0, PSA < 70

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