Radiation treatment for high-grade malignant soft tissue sarcomas (grade III and IV) is administered to optimize local tumor control.
Some patients with high-grade malignant soft tissue sarcoma follow a protocol under testing (SSG XX) with hyperfractionated radiation treatment in addition to chemotherapy.
In some cases of low-grade malignant soft tissue sarcoma (grade I and II), radiation treatment is administered when a possible recurrence will cause a mutilating operation, for example amputation.
Palliative radiation therapy is administered to reduce symptoms from inoperable metastases.
Radiation treatment for soft tissue sarcoma is assessed on an individual basis:
- For inadequate surgery, marginal or intralesional operation, independent tumor depth, where reoperation is not possible
- For deep extramuscular and intramuscular tumors > 5 cm, independent of surgical margins (also for wide margins)
- After surgery for local relapse
- After initial surgery at non-sarcoma center, regardless of margin
- To avoid a mutilating operation
- For symptom-causing metastases
- Cure the disease