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Prognosis of stomach cancer

In 2014, there were an estimated 95,764 people living with stomach cancer in the United States. The earlier stomach cancer is caught, the better chance a person has of surviving five years after being diagnosed. 26.7% are diagnosed at the local stage and the 5-year survival for localized stomach cancer is 66.9%. The number of stomach cancer deaths is highest among people aged 75-84. Death rates have been falling on average 2.4% each year over 2005-2015 (13).

In the western world, 5 year survival is 10–30%, while in Japan it is reported to be 30–40%. This number is considered to include more operated for early gastric cancer. Among those operated curatively, the absolute 5 year survival is about 50%. The prognosis reflects that many are diagnosed late in the disease course.  

5 year survival for:

  • early stage is 70–90%
  • stage II is 30–40 %
  • stage III is 10–30 %

For stage IV, the average survival is about 6 months.

Prognostic factors of importance:

  • degree of surgical radicality (R-stage)
  • degree of tumor infiltration (T-stage)
  • lymph node status (N-stage)
  • occurrence of metastasis (M-stage)  

Raised serological markers CEA and CA 19–9 may be prognostic negatives.

Reporting of oncogenes or other biological markers currently do not have any practical impact.



Five-year relative survival for patients with stomach cancer, in percent, during the diagnosis period 1974–2013.

Source: Cancer Registry of Norway


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