Postoperative adjuvant combined radiation and chemotherapy is assessed for histological resection borders which are not free. However, the survival gain is not well documented (1).
Radiation treatment should be done with three-dimensional dosage planning and include the operation area with nearest lymph drainage area. The total radiation dose is 50 Gy and is combined with 5-FU and calcium folinate or capecitabine.
Patients with a palliative status with symptoms from a primary tumor can have palliative radiation treatment, for example 3 Gy fractions to total dosage 30–36 Gy.